By James Ferrara, H. Joachim Deeg, Kenneth R. Cooke
With precise contributions from greater than forty best specialists at the subject, this 3rd variation comprehensively explores the immunobiology, pathophysiology, and medical manifestations of graft-versus-host illness (GvHD)-offering sections revealing the main up to date examine on immune activation and dysregulation, the pathophysiology of goal organ harm, and GvHD prevention and remedy.
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Sample text
J Allergy Clin Immunol 2000; 106:S40-S44. 122. Baker MB, Riley RL, Podack ER, Levy RB. GVHD-associated lymphoid hypoplasia and B cell dysfunction is dependent upon donor T cell-mediated Fas-ligand function, but not perforin function. Proc Natl Acad Sci USA 1997; 94:1366–1371. 123. Via CS, Nguyen P, Shustov A, Drappa J, Elkon KB. A major role for the Fas pathway in acute graft-versus-host disease. J Immunol 1996; 157:5387–5393. 124. Kondo T, Suda T, Fukuyama H, Adachi M, Nagata S. Essential roles of the Fas ligand in the development of hepatitis.
153. Price KS, Nestel FP, Lapp WS. Progressive accumulation of bacterial lipopolysaccaride in vivo during murine acute graft-versus-host disease. Scand J Immunol 1997; 45:294–300. -host disease 30 154. Morrison DC, Ryan JL. Endotoxins and disease mechanisms. Annu Rev Med 1987; 38:417– 432. 155. Raetz C. Biochemistry of endotoxins. Annu Rev Biochem 1990; 59:129–170. 156. Fegan C, Poynton CH, Whittaker JA. The gut mucosal barrier in bone marrow transplantation. Bone Marrow Transplant 1990; 5:373–377.
Gorham JD, Guler ML, Fenoglio D, Gubler U, Murphy KM. Low dose TGF-beta attenuates IL12 responsiveness in murine Th cells. J Immunol 1998; 161:1664–1670. 86. Dey BR, Yang YG, Szot GL, Pearson DA, Sykes M. Interleukin-12 inhibits graft-versus-host disease through an Fas-mediated mechanism associated with alterations in donor T-cell activation and expansion. Blood 1998; 91:3315–3322. 87. Ellison CA, Fischer JM, HayGlass KT, Gartner JG. Murine graft-versus-host disease in an F1hybrid model using IFN-gamma gene knockout donors.