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British Medical Journal 320: 768-770 Thomas K B 1994 The placebo in general practice. Lancet 344:1066 Urquhart J 2000 Erratic patient compliance with prescribed drug regimens: target for drug delivery I systems. Clinical Pharmacology and Therapeutics 67: 331-334 Vickers A 2000 Complementary medicine. British Medical Journal 321: 683-686 Vickers A, Zollman C 1999 Homeoepathy. British Medical Journal 319:1115-1118 Volmink J, Matchaba P, Garner P 2000 Directly observed therapy and treatment adherence.

Lucid and legible labelling of containers is essential, as well as patient-friendly information leaflets, which are increasingly available via doctors and pharmacists and as package inserts. ) • Poor patient-doctor relationship and lack of motivation to take medicines as instructed offer a major challenge to the prescriber whose diagnosis and prescription may be perfect, but yet loses efficacy by patient noncompliance. e. selfmotivation, to comply. g. in hypertension, where they may be many years away in the future, then doctors must consciously address themselves to motivating compliance.

Report) (see also Ch. 6). • 'Insufficient training in clinical pharmacology. 35 The sheer quantity of new products may lead to a practitioner becoming over-reliant on drugs companies' promotional material, or sticking to "tried and tested" products out of caution based on ignorance' (Report). • Failure of doctors to keep up-to-date (see Doctor compliance). g. by prompting regular review of a patient's medication, by instantly providing generic names from brand names, by giving ready access to formularies and prescribing guidelines.

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