By C. C. Tijssen (auth.), M. Chatel, F. Darcel, J. Pecker (eds.)
The foreign assembly on mind Oncology in Rennes was once organised in honor of Jean Pecker, to pay tribute to his contribution to the advance of neurological sciences and to take inventory of the present nation of data on mind tumors, a website during which the function of neurosurgery has been and should remain primordial. in the course of the two-day convention, the main issues of mind oncology experiences, either primary and medical, have been tested: oncogenesis, tumoral markers and immunology, metabolic and prognosis imaging, prognostic components and healing techniques. the massive quantity and prime quality of participations led to a certainly man made view of present advances in learn, of which this booklet provides the necessities. we've tried either to maintain the richness of medical exchanges which happened and to submit an exceptional many oral and poster communications. The e-book respects the association of convention periods, and therefore displays the significance accorded to glial tumor experiences. this can appear disproportionate given their frequency of prevalence in percentage to overall numbers of intracranial tumor procedures, yet their gravity and quasi-total resistance to present healing equipment are considerable justification. in addition, this is often the area within which hopes of development are commencing to seem, and it's turning into attainable to envisage remedy according to lately proven primary knowledge.
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Extra info for Brain Oncology Biology, diagnosis and therapy: An international meeting on brain oncology, Rennes, France, September 4–5, 1986, held under the auspices of the Ministry of National Education, the University of Rennes and the Regional Hospital Rennes
Patterns of the Early, Gross Chromosomal Changes in Malignant Human Gliomas. Hereditas 101: 103-113 (1984). 9. ): Chromosomal Evolution in Malignant Human Gliomas Starts With Specific and Usually Numerical Deviations. Cancer Genet Cytogenet 22: 121-135 (1986). 10. ): Specific Chromosomal Abnormalities Characterize Malignant Human Gliomas. Submitted (1986). II. ): Amplification Enhanced Expression, and Possible Rearrangement of the EGF Receptor Gene in Primary Human Brain Tumours of Glial Origin.
Brain Research 200, 13-21. 7. ) (1984): Glial fibrillary acidic protein (GFAP) in oligodendroglial tumors. Gliofibrillary oligodendroglioma. and transitional oligoastrocytoma as subtypes of oligodendroglioma. Acta Neuropathologica 64, 265-272. 8. ) (1986): Immunohistochemical characterization of oligodendrogliomas. An analysis of multiple markers. Acta Neuropathologica 72, 15-22. 9. ) (1984): Expression of glial fibrillary acidic protein in immature oligodendroglia. Science 223, 407-409. 10. ) (1979): Astrocytes in hemangioblastomas of the central nervous system and their relationship to stromal cells.
MERCIER ("0) and N. ROST (0). INTRODUCTION Although the cause of cancers is still unknown, experimental data of the last ten years have led to the theory that the abnormal growth pattern typical of cancer is related to changes in the genome of cells (11, 16, 18). The changes can be due to mutations in the gene sequence either spontaneously occurring or due to oncogenic agents (X-rays, chemicals or viruses) (9-14). The altered genes have been demonstrated to be responsible for the induction of malignant transformation in cell cultures or in animals.