Download Kallikrein-Related Peptidases, Volume 2: Novel by Viktor Magdolen, Christian P. Sommerhoff, Hans Fritz, PDF

By Viktor Magdolen, Christian P. Sommerhoff, Hans Fritz, Manfred Schmitt

Numerous KLK proteins and their encoding genes have attracted elevated realization between scientists and clinicians around the globe in view that they symbolize very fascinating and functionally certain biomarkers, relatively, in melanoma. This publication experiences the position of kallikrein-related peptidases (KLKs) in a variety of cancers, together with lung, prostate, breast and ovarian melanoma. It presents clinicians, health practitioner scientists and researchers with a accomplished assessment at the medical relevance of KLK expression in numerous malignancies.

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2008). Human tissue kallikreins as promiscuous modulators of homeostatic skin barrier functions. Biol. Chem. 389, 669–680. P. (2011). Kallikrein-related peptidase-8 (KLK8) is an active serine protease in human epidermis and sweat and is involved in a skin barrier proteolytic cascade. J. Biol. Chem. 286, 687–706. P. (2007). New insights into the functional mechanisms and clinical applications of the kallikrein-related peptidase family. Mol. Oncol. 1, 269–287. P. (2008). Human kallikrein-related peptidase 14 (KLK14) is a new activator component of the KLK proteolytic cascade.

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