Download Handbook of Essential Fatty Acid Biology: Biochemistry, by William A. Banks, Abba J. Kastin, Stanley I. Rapoport PDF

By William A. Banks, Abba J. Kastin, Stanley I. Rapoport (auth.), Shlomo Yehuda, David I. Mostofsky (eds.)

In guide of crucial Fatty Acid Biology: Biochemistry, body structure, and Behavioral Neurobiology, across the world eminent scientists light up crucial medical elements of crucial fatty acids (EFAs)-from their biochemistry to their physiological effects in either future health and affliction. the celebrated members combine quite a lot of themes, together with the elemental biochemistry of EFAs and lipid metabolism, the function of EFAs within the neuronal membrane, the results of EFAs and lipids in a number of ailments, and the results of ordinary degrees and EFA deficiencies on cognition and behaviour.

The instruction manual of crucial Fatty Acid Biology: Biochemistry, body structure, and Behavioral Neurobiology presents the main accomplished survey to be had of our wisdom of the biology and metabolism of fatty acids. It brings jointly various components of biochemistry, habit, and meals, and lays the foundation for dramatic advances in our realizing of those ubiquitous biochemicals and their position in well-being and disease.

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Additional info for Handbook of Essential Fatty Acid Biology: Biochemistry, Physiology, and Behavioral Neurobiology

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1972; Karlsson, 1975). Thus, some meehanism may exist to maintain a eonstant level of polyunsaturated fatty acids in the brain. Bourre et al. (1984) and Bazan et al. (1986a) noted that despite deprivation of these fatty acids, the retina and the brain tenaciously retain 22:6 (n-3). , 1990). Taken together, these observations suggest that doeosahexaenoic acid has an important funetional role in brain and retina. , 1982; Chapman, 1972). Thus, the effect of dietary modulation may have different results on the eomposition of membranes depending on which brain proeess and brain region are developing.

1987). , 1994). Rod outer segments of retinal membrane are thought to be extensions of a nerve ceU plasma membrane (Dowling and Boycott, 1966). , 1986). Generally, cerebroside and sulfatide was not detected, sphingomyelin content was lower (as it is in whole retina and neuronal plasma membranes) and phosphatidylcholine content was higher than plasma membrane from cells in other organs. , 1994). In the photoreceptor membrane, very long-chain fatty acids of C24-C34 have been associated with rhodopsin function (Aveldano, 1988).

Generally, cerebroside and sulfatide was not detected, sphingomyelin content was lower (as it is in whole retina and neuronal plasma membranes) and phosphatidylcholine content was higher than plasma membrane from cells in other organs. , 1994). In the photoreceptor membrane, very long-chain fatty acids of C24-C34 have been associated with rhodopsin function (Aveldano, 1988). Suh et al. (1994) demonstrated that these fatty acids are not of dietary origin, but are synthesized from shorter chain precursors which respond to the dietary n-6/n-3 ratio fed.

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