By A. Bush, K-H. Carlsen, M.S. Zach
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Extra resources for Growing up with lung disease: the lung in transition to adult life
Example text
One potential outcome of dehydration stress is exudation of bulk plasma to restore the airway surface liquid. If the smooth muscle is repeatedly exposed to plasma products that have the potential to alter its contractile properties, then it is likely to become more sensitive to circulating mediators, such as leukotrienes and prostaglandins. In a winter athlete, this could lead to nonspecific BHR and in an atopic athlete the smooth muscle could become passively sensitised and develop BHR to allergens.
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