By Richard G. Dickersin
This article atlas, now in its moment version, provides in least difficult shape the elemental diagnostic standards utilized by the electron microscopist in learning neoplasms and different ailments encountered within the regimen perform of pathology. each box of electron microscopy is roofed and occasional magnification plates are juxtaposed with larger magnifications to demonstrate diagnostic features.The greatest component to the e-book is dedicated to neoplasms as this can be the world within which such a lot diagnostic difficulties ensue. Renal glomerular affliction is one other very important classification within which ultrastructural research could be severe in analysis; infectious ailments, in particular these of viral, protozoan, and strange bacterial etiologies, are a 3rd sector within which electron microscopy can be used to set up or susbstantiate a prognosis. All of those parts are comprehensively lined with concise, readable textual content and greater than 800 first-quality pictures. This e-book is the preeminent reference for pathologists desiring present info at the function of ultrastructure in diagnostic pathology.
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Extra resources for Diagnostic Electron Microscopy: A Text Atlas (2nd Ed.)
Example text
Phyllodes tumor (breast). 3 shows microvilli (V) and junctional complexes (JC). Note also the 31 secretory granules (S), Golgi apparatuses (G), rough endoplasmic reticulum (RER), and mitochondria (M). 5. Adenomatous features at higher magnification. A, Basal lamina (BL). (ϫ 12,150) B, Golgi apparatus (G); rough endoplasmic reticulum (RER), which is dilated and filled with medium-dense material; and secretory DIAGNOSTIC ELECTRON MICROSCOPY: A TEXT/ATLAS granules (S). (ϫ 17,900) C, Golgi apparatuses (G).
Hepatocellular carcinoma (liver). A dilated canaliculus (C) has no remaining microvilli, but tight junctions and junctional complexes (J) as well as innumerable intraluminal granules and vesicles of bile are 37 readily identifiable. Abundant smooth endoplasmic reticulum (S), consisting of many small vesicles, occupies the apical cytoplasm of the bordering hepatocytes. 11. Hepatocellular carcinoma with a Mallory body (liver). This hepatocyte contains a Mallory body (*) composed of intermediate filaments and surrounded by microbodies (peroxisomes) (arrows).
McGraw-Hill, New York, 1976. Dickersin GR: The contributions of electron microscopy in the diagnosis and histogenesis of controversial neoplasms. Clin Lab Med 4:123–164, 1984. Dickersin GR: Embryonic ultrastructure as a guide in the diagnosis of tumors. Ultrastruct Pathol 11:609–652, 1987. Fischman DA: An electron microscopic study of myofibril formation in embryonic chick skeletal muscle. J Cell Biol 32:557–575, 1967. Friedman J, Bird ES: Electron-microscope investigation of experimental rhabdomyosarcoma.