By Jean-Francois Allemand, Pierre Desbiolles
Do you regularly lose your keys? you'll find during this publication the simplest technique to locate them, or not less than the only deduced from statistical physics. what's the hyperlink with biology? a few proteins use an analogous technique to locate their aim inside of a dwelling phone. this instance illustrates one of many many hyperlinks among physics and biology. those hyperlinks consequence from an severe examine task some time past years on the interface among these disciplines. This publication describes one of the most fresh progresses at this interface: from instrumental progresses utilized in biology to the mechanical description of a mobilephone, to molecular automobiles, from mind task mechanisms to auditory or sensory conception. Many fields are coated from the molecular to the size on the organ point. a couple of organic notions are awarded within the first bankruptcy that can aid to entry the organic elements of the others. in spite of everything this booklet may possibly curiosity humans passionate in technology, from the straightforward novice to the complicated researcher level.
Readership: complicated undergraduates and graduate or anybody with a powerful clinical heritage inquisitive about the physics/biology interface.
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Additional resources for Physics and Biology : From Molecules to Life
Example text
For fluorescence imaging, a light source, usually a lamp or a laser, is used to excite the sample whose fluorescence is collected to form an image. In practice, an important benefit of fluorescence imaging lies in the possibility to spectrally discriminate between the excitation and emission light. By means of optical filters placed between the sample and the detector, one selects the emission fluorescence and rejects the excitation light. Just as it is simpler to observe stars at night than during daytime, the sensitivity of fluorescence measurements is largely increased by the fact that detection occurs on a dark background.
The regulation of gene expression and gene duplication still holds many surprises. Bibliography [1] Bruce Alberts, Alexander Johnson, Peter Walter, Julion Lewis, Martin Raff, Keith Roberts. Molecular Biology of the Cell, Garland Publishing Inc. (2007). [2] B. Lemin, Genes IX, Jones and Bartlett Learning (2007). [3] Thomas D. Pollard and William C. Earnshaw, Cell Biology, 2nd Edition, Saunder (2007). 5in b1845-ch02 page 31 2 Fluorescence microscopy for biological imaging Maxime DAHAN, CNRS researcher, Laboratoire Physico-Chimie Curie Institut Curie and CNRS, Paris.
The binding of RNA polymerase to the promoter can be stimulated by an “activator” protein, for instance which will bind just upstream of a promoter to then tether RNA polmerase in the vicinity of the promoter and thus help “recruit” it to the promoter. Other proteins can act as repressors of transcription, for instance by binding on, or near the promoter and preventing RNA polymerase from binding to the promoter, or escaping from the promoter to carry out full gene transcription. g. proteins) can be represented under network form where a gene represents a node and the molecular interactions between the product of that gene and its target represent the connections.