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Extra info for Comprehensive biochemistry / 18,S : Sect. 4, Metabolism, Pyruvate and fatty acid metabolism

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BRESLOW, / . Am. Chem. Soc, 80 (1958) 3719. R. BRESLOW, Ann. N. Y. Acad. , 98 (1962) 445. 19 L. O. KRAMPITZ, I. SUZUKI AND G. GREULL, Ann. NY. 20 L. O. KRAMPITZ, I. SUZUKI AND G. GREULL, Brookhaven Symp. , 15 (1962) 282. Acad. , 98 (1962) 466. 21 P. SCRIBA AND H. HÖLZER, Biochem. , 334 (1961) 473. 22 H. HOLZER, F. DA FONSECA-WOLLHEIM, G. KOHLHAW AND C. W. WOENCKHAUS, 23 Ann. NY. Acad. , 98 (1962) 453. H. W. GOEDDE, K. G. BLUME AND H. HOLZER, Biochim. Biophys. Acta, 62 (1962) 1. 24 H . W. GOEDDE, B.

Under these conditions citrate uptake is inhibited by oligomycin, presumably because this substance prevents the generation from ATP of the energy-rich intermediates which are involved in the accumulation process. The energy-linked uptake of citrate shows a requirement for a dicarboxylic acid such as malate 230 . This indicates that tricarboxylate permease is involved in the uptake of citrate even when the process is energy-dependent. The general properties described for citrate uptake coincide with those observed for cation uptake.

KALNITSKY, / . Biol. , 207 (1954) 605. 107 J. A. SHEPHERD, Y. W. L I , E. E. MASON AND S. E . ZIFFREN, / . Biol. , 213 108 (1955) 405. M . R . V. MURTHY AND D . A. RAPPOPORT, Biochim. Biophys. Ada, 74 (1963) 51. 109 W. R . FRISELL, M . V. PATWARDHAN AND C. G . MACKENZIE, / . Biol (1965) 1829. , 240 52 PYRUVATE DEHYDROGENASE AND CITRIC ACID CYCLE I 110 J. L. PURVIS, Biochim. Biophys. Acta, 30 (1958) 440. 111 G. W. E. PLAUT AND S. C. SUNG, J. Biol. , 207 (1954) 305. 112 L. ERNSTER AND F. NAVAZIO, Exptl.

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