By Trudy McKee, James R. McKee
This textbook is for a various viewers starting from chemistry majors to scholars in any of the lifestyles sciences. The logical association - dialogue of molecular constitution instantly by way of the position it performs in metabolism - leads scholars in the course of the advanced international of biochemistry whereas a powerful artwork application is helping to steer them via updated ideas.
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BRESLOW, / . Am. Chem. Soc, 80 (1958) 3719. R. BRESLOW, Ann. N. Y. Acad. , 98 (1962) 445. 19 L. O. KRAMPITZ, I. SUZUKI AND G. GREULL, Ann. NY. 20 L. O. KRAMPITZ, I. SUZUKI AND G. GREULL, Brookhaven Symp. , 15 (1962) 282. Acad. , 98 (1962) 466. 21 P. SCRIBA AND H. HÖLZER, Biochem. , 334 (1961) 473. 22 H. HOLZER, F. DA FONSECA-WOLLHEIM, G. KOHLHAW AND C. W. WOENCKHAUS, 23 Ann. NY. Acad. , 98 (1962) 453. H. W. GOEDDE, K. G. BLUME AND H. HOLZER, Biochim. Biophys. Acta, 62 (1962) 1. 24 H . W. GOEDDE, B.
Under these conditions citrate uptake is inhibited by oligomycin, presumably because this substance prevents the generation from ATP of the energy-rich intermediates which are involved in the accumulation process. The energy-linked uptake of citrate shows a requirement for a dicarboxylic acid such as malate 230 . This indicates that tricarboxylate permease is involved in the uptake of citrate even when the process is energy-dependent. The general properties described for citrate uptake coincide with those observed for cation uptake.
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