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By Olga Petre-Quadens

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Spindles and interspindle lulls (EEG synchronization) in the acute cerveau isole cat. Parietal (P) and occipital (O) left (L) and right (R) leads. B. EEG desynchronization, 5 min after intracarotid injection of 10 mg of dopa. C. Synchronized pattern 2 hr after B (and 5 min after intravenous injection of 10 mg of dopa). The effect of the intravenous injection (slight increase of the interspindle lulls) is much smaller than that of the intracarotid injection. LFrom Mantegazzini and Glässer, i960] should be transformed, locally, into the noradrenaline mediator.

Note lack of arousing effect in A, and the short-lasting arousal (opening of the eyes, © Θ, and increase in heart rate) in B, C and D. Same as in A and B, but during bow-cooing elicited by tactile stimulation. Note in both records the reversible blockade of bow-cooing and the decrease of heart rate. 8 V). Time calibration applies to all records. , 1972] 43 500 Γ 460 Γ 420 Γ # 380 Γ 340 L * · " . * 3°° Ε . · 260 I 220 Γ 180 L * · · . # . · '*» ¥ ΐ'ι^"ι*ιϋΜ<ι»*> 'ΦΦ1^"' ΜΜ\*\Ηηώ*Μ » '#|Ι ■' I ^ φ ' I' Β 340 300 260 220 180 140 L L L L L # .

Note the absence of arousal in D and a clear-cut arousal in E, shown by the opening of the eyes (Θ θ ) and by the increase in heart rate. Time calibration applies to all records. ] the neck and exploratory movements of the head. Nevertheless, the arrest of waking activity and the behavioral arousal are elicited at different threshold intensities of stimulation. 8 V). It might of course be suggested that the same system is likely to have a lower excitability during sleep than during wakefulness.

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