By Herman S. Overkleeft, Bogdan I. Florea
This quantity specializes in explorative activity-based proteomics,biomedical purposes of activity-based proteomics, and chemical ideas in activity-based proteomics supplying a concise review of activity-based protein profiling. Written within the hugely profitable Methods in Molecular Biology series structure, chapters contain introductions to their respective issues, lists of the mandatory fabrics and reagents, step by step, without difficulty reproducible laboratory protocols, and tips about troubleshooting and fending off recognized pitfalls.
Authoritative and state of the art, Activity-Based Proteomics: tools and Protocols goals to make sure winning ends up in the additional research of this important field.
Read or Download Activity-Based Proteomics: Methods and Protocols PDF
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Extra info for Activity-Based Proteomics: Methods and Protocols
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26. 27. 28. 29. 30. 31. 32. 45 Nat Chem Biol 5(9):616–624. 216 Rappsilber J, Mann M, Ishihama Y (2007) Protocol for micro-purification, enrichment, pre-fractionation and storage of peptides for proteomics using StageTips. Nat Protoc 2(8):1896–1906. 261 White K, Bruckner JV, Guess WL (1973) Toxicological studies of 2-mercaptoethanol. J Pharm Sci 62(2):237–241 Zikolov P, Budevsky O (1973) Acid-base equilibria in ethylene glycol--I: definition of pH and determination of pk-values of acid-base indicators.
012 Jaffrey SR, Snyder SH (2001) The biotin switch method for the detection of S-nitrosylated proteins. Sci STKE 2001 (86):pl1. pl1 Hang HC, Linder ME (2011) Exploring protein lipidation with chemical biology. Chem Rev 111(10):6341–6358. 1021/ cr2001977 Weerapana E, Wang C, Simon GM, Richter F, Khare S, Dillon MBD, Bachovchin DA, Mowen K, Baker D, Cravatt BF (2011) Quantitative 22 Yu Qian and Eranthie Weerapana reactivity profiling predicts functional cysteines in proteomes. Abstr Pap Am Chem Soc 241 15.
J Nat Prod 72(1):14–17. 1021/np8003529 15. Conroy T, Guo JT, Linington RG, Hunt NH, Payne RJ (2011) Total synthesis, stereochemical assignment, and antimalarial activity of gallinamide A. Chemistry 17(48):13544–13552. 201102538 16. Conroy T, Guo JT, Hunt NH, Payne RJ (2010) Total synthesis and antimalarial activity of symplostatin 4. Org Lett 12(23):5576– 5579. 1021/ol1024663 17. Stolze SC, Deu E, Kaschani F, Li N, Florea BI, Richau KH, Colby T, van der Hoorn RA, Overkleeft HS, Bogyo M, Kaiser M (2012) The antimalarial natural product symplostatin 4 is a nanomolar inhibitor of the food vacuole falcipains.