By Sun Hongmao
This ebook will not be an exhaustive survey protecting all features of rational drug layout. as an alternative, it will offer serious knowledge via real-world examples. proper case experiences might be offered and analyzed to demonstrate the subsequent: how you can optimize a lead compound even if one has excessive or low degrees of structural info; how you can derive hits from opponents' energetic compounds or from average ligands of the objectives; tips on how to springboard from rivals' SAR wisdom in lead optimization; how one can layout a ligand to intervene with protein-protein interactions via appropriately analyzing the PPI interface; tips to evade IP blockage utilizing facts mining; the way to build and entirely make the most of a knowledge-based molecular descriptor process; tips to construct a competent QSAR version via concentrating on info caliber and correct collection of molecular descriptors and statistical ways. a pragmatic advisor to Rational Drug layout specializes in computational drug layout, with purely simple assurance of biology and chemistry concerns, reminiscent of assay layout, aim validation and artificial routes. Read more...
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We do really want this ebook because the legislations of facts is turning into one big DNA try in lots of fields the place the defence insists on difficult uncomplicated actual statements (on directions from the customer, of course).
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Additional info for A practical guide to rational drug design
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