By Christine A. Orengo, Alex Bateman, Vladimir Uversky
New insights into the evolution and nature of proteins
Exploring a number of unique techniques, this e-book describes the tools for evaluating protein sequences and protein buildings which will determine homologous relationships and classify proteins and protein domain names into evolutionary households. Readers will realize the typical good points in addition to the main philosophical ameliorations underlying the key protein category structures, together with Pfam, Panther, SCOP, and CATH. in addition, they are going to become aware of how those platforms can be utilized to appreciate the evolution of protein households in addition to comprehend and are expecting the measure to which structural and useful details are shared among kin in a protein family.
Edited and authored through top foreign specialists, Protein Families deals new insights into protein households which are very important to scientific study in addition to protein households that support us comprehend organic structures and key organic procedures corresponding to telephone signaling and the immune reaction. The ebook is split into 3 sections:
- Section I: suggestions Underlying Protein kin Classification reports the main techniques for deciding on homologous proteins and classifying them into families.
- Section II: In-Depth experiences of Protein Families makes a speciality of a few interesting large protein households for which we now have titanic quantities of series, structural and sensible info, making it attainable to track the emergence of functionally various relatives.
- Section III: evaluation of Protein households in vital organic Systems examines protein households linked to a specific organic subject, similar to the cytoskeleton.
All chapters are commonly illustrated, together with depictions of evolutionary relationships. References on the finish of every bankruptcy consultant readers to unique examine papers and experiences within the field.
Covering protein kinfolk category structures along distinct descriptions of decide upon protein households, this publication bargains biochemists, molecular biologists, protein scientists, structural biologists, and bioinformaticians new perception into the evolution and nature of proteins.